Isoproturon is non-persistent in soil; very photochemically stable, and stable to acids and alkalis,[1] but under sustained ultraviolet light can degrade into some eleven products,[5] and can be hydrolytically cleaved by strong bases on heating.[1]
Degradation is mainly N-demethylation and oxidation of the ring-isopropyl group. Variations in order give rise to a few possible pathways, and the balance of demethylation and oxidation can allow selective activity of the herbicide. Both reactions may occur, making a typical degradation product of 2-(4-Aminophenyl)propan-2-ol (also called Dimethyl-p-Aminobenzylalkohol),[5] which is an irritant and may be harmful if swallowed.[18]
Most isoproturon is expected to have degraded in soil after 6-28 days; the rate is temperature sensitive as the process is driven by enzymes and microbes.[1] In water, the DT50 is 40 days, and in water sediments 149 days.[7]
Metabolism in plants usually follows the path beginning with isopropyl side chain oxidation.[5] White-rot fungus has the lignin-degrading enzymes lignin peroxidase and manganese peroxidase which are known to degrade



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